
Thousands Are Feeling the Difference
What Makes Plique Different
What To Expect
Your Journey to Calmer Nerves
Consistency is everything. Here is what most people feel, week by week.
Easy Start
The simplest part of your day.
- Two softgel a day, taken with a meal
- No brain fog, no weight gain, no grogginess
- Gentle on the stomach, easy to stay consistent
Support Begins
The R-ALA reaches where it matters.
- Crosses the blood-nerve barrier to the mitochondria
- Many report better, deeper sleep
- The daily habit starts to feel automatic
Comfort You Can Feel
The stretch most people talk about.
- Greater comfort in feet and legs reported by many users*
- Supports healthy nerve signaling and cellular function*
- Quality-of-life improvements, no withdrawal worries
Long-Term Nerve Health
Where staying consistent pays off.
- Ongoing nerve and mitochondrial wellness support*
- Cellular resilience through antioxidant protection*
- A routine that targets the root cause, not just symptoms
How It Works
Support That Reaches Your Nerves
Your nerves run from your spine to your feet, and that is where the burning and tingling begin. Plique R-ALA crosses the blood-nerve barrier to reach the mitochondria inside your nerve cells, supporting healthy nerve function at the
Discover Why the German Medical Community Has Used R-ALA Since 1966
Learn what makes Plique R-Alpha Lipoic Acid different.
Why Gabapentin Leaves Your Nerves Still Dying, While You Feel Like a Zombie
Gabapentin does not repair your nerves. It was never designed to.
It is a sodium-channel blocker, meaning it works by silencing the nerve signal that is screaming at you. The fire is still burning. You just cannot hear the alarm anymore. That is why the brain fog sets in. That is why the weight creeps up. That is why the pain comes roaring back the moment a dose wears off. And that is why, even after months or years on gabapentin, your neuropathy keeps getting worse.
R-Alpha Lipoic Acid works on an entirely different mechanism. It crosses the blood-nerve barrier, reaches inside the mitochondria of your nerve cells, and neutralizes the oxidative stress that high blood sugar creates. It does not silence the alarm. It puts out the fire.
- No brain fog, R-ALA does not block signals across your entire nervous system
- No weight gain, unlike gabapentin and Lyrica, R-ALA is weight neutral
- No withdrawal, miss a day and nothing happens
- Addresses the root cause gabapentin ignores
Plique R-ALA: Real Support for Burning, Tingling Nerves
For decades, people with diabetic neuropathy have been told the same thing: take gabapentin, control your blood sugar, and learn to live with it.
Plique offers something different. Each softgel delivers 600mg of pure R-Alpha Lipoic Acid, the exact form and dose used in German clinical trials, formulated with coconut oil for maximum absorption, and designed to support your nerves at the source, not just silence the signal.
- Supports healthy mitochondrial function in nerve cells
- Antioxidant support for nerves affected by high blood sugar
- No brain fog. No weight gain. No withdrawal.
Pure R-Form. Clinical Dose. Nothing Else.
Most alpha lipoic acid supplements sold at Walmart and Amazon are a 50/50 racemic mix, half R-form, half S-form. The S-form is a synthetic byproduct that may actually compete with the R-form for absorption.
Plique uses only pure R-(+)-Alpha Lipoic Acid, the biologically active form your body recognizes, at the full 600mg clinical dose, formulated with coconut oil to maximize bioavailability.
- 100% pure R-form, zero S-isomer
- 600mg per serving, matches the ALADIN and SYDNEY trial dose
- Formulated with coconut oil for enhanced absorption
- No fillers, no artificial dyes, no unnecessary additives
Backed by 60 Years of German Prescription Use and 4 Major Clinical Trials
R-Alpha Lipoic Acid is not a new supplement trend. It was approved as a prescription drug in Germany in 1966 for diabetic neuropathy, nearly 60 years before most American doctors had heard of it.
The ALADIN, SYDNEY, and NATHAN clinical trials tested it on over 4,000 patients. The results were consistent: a significant reduction in burning, tingling, and numbness, with minimal side effects and no brain fog, no weight gain, no withdrawal.
It works differently than gabapentin. Instead of blocking the pain signal, R-ALA crosses the blood-nerve barrier, penetrates the mitochondria inside your nerve cells, and neutralizes the oxidative stress that high blood sugar creates, addressing the root cause, not just the symptom.
- German prescription drug since 1966
- 4 major clinical trials, 4,000+ patients
- Crosses the blood-nerve barrier and penetrates the mitochondria
- Backed by our 90-day money-back guarantee
Unlike Gabapentin, Plique Supports Your Nerves at the Source
Formulated with pure R-form alpha lipoic acid to support healthy nerve function, mitochondrial energy, and everyday antioxidant protection. It uses only the biologically active R-(+) form, none of the inactive S-isomer that blocks absorption in ordinary ALA, so more of every dose reaches your nerves.
The Difference
Plique vs Other Brands
90-Day Money-Back Guarantee. If you do not feel a difference, you pay nothing.
Before You Ask
We're serious about nerve health. Ask away.
Honest answers to the questions we hear most.
This is the most common thing we hear, and there is a real reason it did not work.
Almost every ALA supplement sold at Walmart, Amazon, or the big chains is a 50/50 "racemic" mix of two mirror-image forms: the R-form and the S-form. Only the R-form is biologically active, it is the one your body makes naturally. The S-form is a synthetic byproduct that does nothing, and it can actually compete with the R-form for absorption, blocking it from getting in.
So if you took regular ALA and felt nothing, you were likely absorbing a fraction of an already under-dosed pill. Plique is 100% pure R-form at the full 600mg, wrapped in coconut oil so far more of every dose actually reaches you.
We understand the skepticism, and we will not promise you overnight results.
Most people notice a difference in burning, tingling, and numbness within 3 to 5 weeks. Some feel changes in the first week or two. Others take the full 8 weeks. The key is consistency, R-ALA works gradually by supporting your nerve cells from the inside, and that process takes time.
We recommend committing to at least 8 weeks. That is why every order is backed by a 90-day money-back guarantee, so you have the full time it needs, with zero financial risk.
This is completely understandable, and the answer has nothing to do with whether it works.
R-Alpha Lipoic Acid has been used in Germany as a prescription treatment for nerve health since 1966. German doctors have relied on it for nearly 60 years. But in the United States it has never gone through the FDA drug-approval process, not because it is unsafe or ineffective, but because it is a naturally occurring compound that cannot be patented.
No patent means no company will spend hundreds of millions on approval trials, and no approval means no sales reps introducing it to your doctor. Your doctor is not withholding anything. They were simply never trained on a compound no one profits from teaching.
Two softgel daily with a meal. That is it. No handful of pills, no complicated routine. Taking it with food helps absorption.
R-Alpha Lipoic Acid on its own is water-soluble, so a lot of it passes straight through you. Coconut oil makes it fat-soluble, so it crosses into your bloodstream and actually reaches your nerves. That is what makes Plique roughly twice as bioavailable as standard ALA.
R-ALA is generally very well tolerated and fits easily into most daily routines.
The main thing to be aware of: if you take insulin or diabetes medication, R-ALA can affect blood sugar, so your doctor may want to monitor your levels. We always recommend letting your doctor know you are adding R-ALA, most will have no objection.
Never stop or reduce a prescription medication without consulting your doctor first.
One active: pure R-Alpha Lipoic Acid at 600mg. Other ingredients are coconut oil, gelatin, glycerin, and purified water. It is non-GMO, gluten-free, third-party lab tested, and made in a GMP-certified facility in the USA. No fillers, no artificial dyes.
We offer a full 90-day money-back guarantee, no fine print, no hoops to jump through.
Here is why we are confident enough to offer it: R-ALA has decades of safety behind it and a long clinical track record. We have formulated it at the exact dose and purity that track record is built on. If you take it consistently for 8 weeks and do not feel a real difference in your burning, tingling, or sleep, contact us for a full refund. No questions asked.
We would rather earn your trust than keep your money.